Physiology and Medications of the Lumbar Disc Disease

Lumbar dish aerial unsoundness, as the name implies, is a disease attacking the lumbar field of the spinal anesthesia column that is characterized by general pain, weakness, and numbness in either section of the lumbar areafive segments in the lower extremities of the spinal column and the record connecting them or the intervertebral disc. Lumbar Disc Disease is often used interchangeably with the following associated medical terms sciatica, lumbosacral radiculopathy (or simply radiculopathy), LBP (Lower Back Pain), (LRS)lumbosacral radicular syndrome, and herniated disc.Technically speaking though LRS or radiculopathy would be descriptive of the more specific leg pain or the sciatica. Physiology of the disease involves the breaking, herniated, or bulged condition of the intervertebral disc caused by disc concretion through dehydration in the affected discoid area and go with by bulging bulge out of nucleus pulposus and degeneration of the annulus fibrosis. progress disc degeneration can lead to herniated condition whereby the nucleus pulposus ruptures from the outermost ring region and effecting metric weight unit or press on the crude nerves sublocated between disc spaces or the lumbar epidural spaces.Due to the weight or the press, the affected person experiences pain in the same region. The impingement on the nerve roots or the sinuvertebral nerves caused neurologic symptoms in the regions that are supplied by the affected nerves. Disc herniation unremarkably attacks between the fifth and the 4th lumbar bodies (L4-5) and the fifth lumbar be and the immediate sacral region (L5-S1). Size of the disc herniation is digressive to the severity of the symptoms of the radiculopathy.Inflammation from the disc hernia may also have resulted from increase activity of the phospholipase A2, nitric oxide, prostaglandin E, leukotriene B4 and thromboxane B2 in the disc region as caused by the hernia initiating nociceptive and inflammatory responses. Suc h disease is a honey oil ailment in the elderly or the aging individuals. It occurs on four per cent of the US population with ages from 40 to 60 for both priapic and female gender.Specific symptoms of the disease are dependent on the lumbar disc press on the specific nerve ends and may include any(prenominal) or a combination of the following (1) intermittent or free burning back pain, (2) back muscle spasm, (3) sciatica, (4) muscle weakness/numbness in the lower extremities, (5) decreased joint reflexes, and (6) possible bladder malfunction. Symptoms may carry for more than a month. The disease is diagnosed through medical history examination, natural examination, x-ray diffraction, magnetic resonance imaging (MRI), Computed tomography (CT) scanning, Discography, Myelogram and Electrodiagnosis (e.g. bespeakle electromyography). neurological and musculoskeletal systems possible dysfunctions are observed soundly to detect sensory or motor deficits. As of recent, lumbar disc disease treatment would include conservative therapy (non- secret agent) physical therapy (e. g. L5 reflex assessment), emphasise reduction programs, lumbosacral back support, weight management and medications for alleviating the painful symptomsand operative therapy or the surgical process or removal of the affected lumbar region, otherwise known as lumbar disketomy.In a study for the assessing the efficacy of surgery for lumbar disc disease conducted by Weinstein and colleagues in 2006, it was found out that both operative and non-operative therapy for curing the disease demonstrated substantial forward motion in their conditions, however, the authors, did not indicate which therapy is more effective downplaying it to statistical insignificance. Bibliography Herniated heart Pulposus (Slipped Disk) (2006). Retrieved January 10, 2008 from http//health. nytimes. com/health/guides/disease/herniated-nucleus-pulposus-slipped-disk/overview. htmlLumbar Disc Disease (Herniated Disc) . Retrieved January 10, 2008 from http//www. ohsu. edu/health/health-topics/topic. cfm? id =8838. Malanga, G. (2007) Lumbosacral Radiculopathy. Retrieved January 10, 2008 from http//www. emedicine. com/SPORTS/topic66. htm Weinstein, J. et al. (2006). surgical vs Nonoperative Treatment for Lumbar Disk Herniation. JAMA,. 2006, 2962441-2450. Retrieved January 10, 2008 from http//jama. ama-assn. org/cgi/content/full/296/20/2441 What You Need to Know About Sciatica. (2007) Retrieved January 10, 2008 from http//www. spine-health. com/topics/cd/d_sciatica/sciatica. html